The world's oldest documented case of cancer hails from ancient Egypt, in b. The details were recorded on a papyrus, documenting 8 cases of tumors occurring on the breast. It was treated by cauterization, a method to destroy tissue with a hot instrument called "the fire drill". All Rights Reserved. The material on this site can not be reproduced, distributed, transmitted, cached or otherwise used, except with prior written permission of Multiply.
HER2’s Genetic Link to Breast Cancer Spurs Development of New Treatments
Discovery of Breast Cancers Within 1 Year of a Normal Screening Mammogram: How Are They Found?
Breast cancer is the most common cancer in women around the world. It has been widely studied throughout history. In fact, research on breast cancer has helped pave the way for breakthroughs in other types of cancer research. But other findings and treatments have remained the same for years. Read on to learn how breast cancer treatments have evolved to what we know today. Humans have known about breast cancer for a long time. For example, the Edwin Smith Surgical Papyrus describes cases of breast cancer.
History of cancer
Breast cancer is cancer that develops from breast tissue. Risk factors for developing breast cancer include being female, obesity , lack of physical exercise, drinking alcohol , hormone replacement therapy during menopause , ionizing radiation , early age at first menstruation , having children late or not at all, older age, prior history of breast cancer, and family history. The balance of benefits versus harms of breast cancer screening is controversial.
When NCI-supported researchers discovered that the HER2 gene is important for breast cancer growth, this led to the development of the drug trastuzumab and other targeted treatments that have improved survival for women with HER2-positive breast cancer. For years, doctors and researchers have noted that not all cancers are alike. But for other patients, their tumors grow rapidly and spread like wildfire. In the early s, after the discovery that a mutated gene called HER2 could stimulate excessive cell growth and division, many scientists wondered if certain genes might make cancers grow and spread rapidly. Researchers around the world began searching for genes that spur cancer growth.